Physician Profile

Geoffrey Pitt, MD, PhD

Education:
Medical School:
Johns Hopkins University, Maryland 1993 - MD

Residency:
Internal Medicine, Stanford University Hospital, California, 1995

Fellowship:
Cardiovascular Disease, Stanford University Hospital, California, 1999

Other Degrees:
Ph.D., Biochemistry, Cellular, and Molecular Biology, Johns Hopkins University, Maryland, 1993

Clinical Interests:
General cardiology with a special interest in inherited cardiovascular diseases and arrhythmias

Research Interests:
Our research focuses on how intracellular Ca2+, the ultimate signal of membrane excitability, regulates membrane excitability and the consequent function of excitable cells. We have discovered and described multiple mechanisms that control Ca2+ influx through voltage-gated Ca2+ channels and feedback mechanisms by which internal calcium regulates other channels that influence Ca2+ channel function. The work has entailed structure-function analyses of ion channels and their regulatory subunits and studies of mutations that lead to inherited channelopathies such as cardiac arrhythmias and epilepsy.